This article gives a few settings that I've found useful.
Akeeba backup and kickstart was a good way to upload the site.
You do not need the FTP layer for normal file transfer.
Email configuration took some working out, but I found a working solution on the internet. It is NOT the same server configuration you need to access the 1&1 servers from a home PC.***
Send mail - YES
Mailer - SMTP
From email: (a valid email address on your 1&1 hosting account)
From name: (a name you want shown as the email originator, e.g. "website")
SMTP authentication - Yes
SMTP security - None
SMTP port - 25
SMTP username - (the same valid email address)
SMTP password: (the correct password for this mail account)
SMTP host: smtp.1and1.com
*** 1&1 advertise Joomla hosting: it's not like I'm doing something unexpected. Hiding the correct configuration from you isn't good enough - shame on you 1&1